A Study on In-vitro Anti-Inflammatory and Antioxidant Activity of Aqueous Extract of Terminalia chebula

Abstract

During ancient times, naturally occurring herbs were a remedy for various ailments in the human body. The deciduous trees of Terminalia species are native to south Asia to southeast China, known as black-chebulic myrobalan. Parts of Terminalia chebula are comprehensively used as medicinal properties. Antioxidants play a noteworthy role by hindering the oxidation reaction, which prompts neurodegenerative disorders in humans. Antioxidant and anti-inflammatory qualities originate from plants. T. chebula has lavish phytochemical properties such as tannins, flavones, essential oils, and phenolic compounds, which give rise to countless possessions like anticancer, antibacterial, anti-inflammatory, and antioxidant activity. The antioxidative capacity of T. chebula fruit aqueous extracts have been assessed using the DPPH scrutiny. The purpose of the study is to get an aqueous extract of T. chebula that contains anti-inflammatory and antioxidant compounds. The concentrations were measured by using absorbance at wavelength 517 nm. The aqueous extracts of T. chebula fruits were considered with a 10 to 50 mL range (5 concentrations). Using %inhibition, 55% at the lowest concentration (10 μL) and 84% at high concentration (50 μL) shows antioxidant activity. The active extracts of T. chebula fruits demonstrate the anti-inflammatory effects of using BSA as a reagent. This assay measured the activity using 5 concentrations (10–50 mL). 75% at 10 μL and 90% at 50 μL concentration attained the anti-inflammatory activity. The study exhibits that the higher the concentration, the higher the activity. The extraction of these active compounds has active principles and novel research activities on anti-inflammatory and antioxidant properties..