Abstract
Background : Nasal Polyp is commonly encountered in clinical practice and important from clinical and pathological perspectives as they have varieties of histological patterns. The Polypoidal masses in nasal cavity form a complex group of lesions with wide spectrum of histopathological features, mainly grouped under allergic and inflammatory. Histopathological examination shows a spectrum of lesions ranging from the non-neoplastic ones to neoplastic tumors. Methods: Present study included 153 polypoidal lesions of the nasal cavity during a period of one year. All the tissues were fixed in 10% buffered formalin, processed, stained with H & E and studied for various histopathological patterns. Periodic acid Schiff’s and reticulin stains were used wherever necessary. Results: classifying the sinonasal lesions according to histo-pathological features into various types helps us to know the clinical presentation, treatment, clinical outcome and prognosis of the disease. Although most of nasal polyps sent for histopathology are inflammatory, secondary to infection or allergy, various benign and malignant lesions of nose may present as polypoidal masses, Conclusion: The study recommends, all polyps need histo-pathological examination. DOI: 10.21276/APALM.1173
Highlights
Sinonasal lesions are the common lesion encountered in clinical practice and important from clinical and pathological perspectives as they give rise to varieties of histological patterns and grades of malignancies. [1] The presence of mass in the nose is a seemingly simple problem; it raises numerous questions about differential diagnosis
The true nasal polyps are the tumor like nonneoplastic polypoid masses arising from nasal cavity and sinuses, classified interms of Allergic nasal polyp, which constitutes 85-90%, Fibroinflammatory polyp characterized by chronic inflammation and metaplastic changesof the overlying epithelium
Among Non-neoplastic lesions (n=98), allergic Nasal polyp cases were high with 56.12%
Summary
Sinonasal lesions are the common lesion encountered in clinical practice and important from clinical and pathological perspectives as they give rise to varieties of histological patterns and grades of malignancies. [1] The presence of mass in the nose is a seemingly simple problem; it raises numerous questions about differential diagnosis. Neoplasms of the nose and paranasal sinuses are not common, they are of interest because of their various types. Sometimes, it becomes quite impossible to distinguish between inflammatory conditions presenting as simple polyps, polypoidal lesions due to specific disease and polypoid neoplasm (benign and malignant). Nasal polyps are defined as prolapsed lining of the nasal sinuses. They are essentially rounded projections of edematous membrane. Tumors of various type have a tendency to become polypoid. An epithelial papilloma of the nasal cavity often resembles a nasal polyp.[5] Some lesions are specific to certain location, for e.g., epithelial papilloma of turbinate, juvenile angiofibroma of nasopharynx. The current study initiated to determine the Hisotopathological variations to categorize nasal polyps which are difficult to identify by clinical findings
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
