A STUDY ON HEAMPHILUS INFLUANZAE TYPE B DISEASE CAUSING ANTIGENS: AN APPROACH OF EPITOPE PREDICTION, ANTIGENICITY AND IMMUNOGENICITY PREDICTION

Abstract

Vaccines work by mimicking disease agents and stimulating the immune system which in turn builds a defence mechanism against the disease causing agents. Some of the vaccines contain a part of the disease causing agents which are either weakened or dead. Apart from using vaccines only for viral infections, utilizing the same against Cancers both as therapeutic and preventative has captured huge interest. The use of Cancer vaccines in cancer therapies is called immunotherapy which is done either by specific cancer vaccine or universal cancer vaccine which contain tumour antigens that stimulate the immune system which in turn initiate various mechanisms that terminate tumour cells and prevents recurrence of these tumours. Hemophilus influanzae is a disease causing virus & here we have done a brief study about the different antigens of the b strain of Haemophilus influenzae and compare them using various bioinformatics tools to get the most effective antigen of the above mentioned strain.