Abstract
目的 研究乙肝感染孕妇注射抗体后其母乳HBV-DNA含量变化.方法抽取至少一项乙肝血清学标记(HBsAg)阳性且肝功能正常产妇86人孕期已注射乙肝抗体600μg为实验组,86例未注射抗体为对照组,采用PCR技术检测其乳汁中HBV-DNA含量.结果实验组乳汁检测阳性4例,占4.6%.对照组乳汁阳性18例占32%.(P＜0.05)结论乙肝感染孕妇注射抗体后其乳汁HBV-DNA含量显著下降,对HBeAg阴性的产妇注射抗体后其母乳基本安全,而HBeAg阳性的产妇哺乳前最好进行乳汁的检测以切断母婴传播途径,降低我国乙肝患病率。
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