A Study on Etiology, Severity, Management and Outcome of Acute Pancreatitis in Tertiary Care Teaching Hospital

Abstract

Acute pancreatitis is thought to be a local inflammatory process involving premature intra-cellular activation of digestive enzymes within acinar cells leading to auto digestion of the tissue that can progress to involve distant organs. AP was one of the most common diseases in gastroenterology. Practical understanding of etiology and severity will accommodate in advocate the appropriate treatment. The aim of our study was to provide safe and effective management by evaluating the cause, severity and appropriate treatment and outcomes in patients with AP. General Medicine department Rajiv Gandhi Institute of Medical sciences, a south Indian tertiary care teaching hospital Kadapa, Andhra Pradesh. A prospective interventional study was conducted in 60 patients with AP. Data collected from 60 patients was initially assessed for isolation of etiology by using specially self designed etiology assessment form, severity based on Atlanta severity assessment scale (ASAS). Treatment was given according to American college of gastro enterology(ACG) guidelines, and outcome was measured in terms of length of stay in hospital. Out of 60 patients 24(40%) patients with alcohol, 33(55%) with alcohol and smoking, 3(5%) with gall stones. On severity assessment 42(70%) patients were mild and 18(30%) were moderate. On measurement of outcomes 23(38.3%) patients were better, 25(41.6%) patients were moderate, and 7(11.6%) patients were poor control. we conclude that evaluating cause, severity and management based on the standard guidelines are found to be the safe and effective management of AP to reduce the hospital stay.