A STUDY ON ELECTROCARDIOGRAPHIC AND ECHOCARDIOGRAPHIC CHANGES IN CHRONIC KIDNEY DISEASE

Abstract

Background- Patients with Chronic Kidney Disease exhibit an elevated cardiovascular risk manifesting as Coronary Artery Disease , heart failure, arrhythmias and sudden cardiac death. CKD causes a systemic, chronic pro-inammatory state contributing to vascular and Myocardial remodeling processes resulting in atherosclerosis sclerotic lesions, vascular calcication as well as brosis and calcication of cardiac valves. In this respect, CKD mimics an accelerated aging of the cardiovascular system. Total Procedurenumber of 80 cases including both male and female who presented With CKD in Postgraduate Department of General Medicine JLNMCH was taken in study. The duration of study is two years. Study design is hospital based observational prospective study. In inclusion criteria of cases with GFR 30 - 59 ml/min, bilaterally contracted kidney with poor CMD on USG. Patients with established CKD irrespective of etiology was taken into account. In all patients detailed history of illness, all blood biochemical investigations ECG, ECHO and USG were performed, and analysis was done accordingly. CKD is increasingly recognized as a global publ Conclusion- ic health problem imposing huge medical and nancial burden on society and Healthcare systems with an estimated prevalence of 13.4% globally. Control of traditional risk factors as well as antiplatelet therapy are cornerstones to reduce cardiovascular risks. The effect of lipid-lowering strategies on CV risk reduction in CKD seems to be dependent on severity of CKD (SHARP STUDY).