A study on cognitive function after ischemic basal ganglia's stroke

Abstract

Objective To find the correlation factors of cognitive disorder after ischemic basal ganglia's stroke. Methods 46 cases of ischemic basal ganglia's stroked patients by MRI. And 46 cases health control were tested by Wechsler Adult Intelligence Scale (WAIS),Wechsler Memory Scale (WMS),Trail Making Test A and B,Wisconsin Card Sorting Test (WCST).t test,chi-square,two independent samples and spearmancorrelation were used to analyze the data. Results 1)Group of thalamic stroke compare with health control for recognition index,there were significant different between the two groups,there were higher score in the stroke group at trail making test A (54.04±5.66),Executive complete number of categories (Cc)(3.56±0.12),Executive error responsive number (Re)(16.17±0.58),non Executive persist error number.Contrary at vocabulary(54.21±2.73),Undergoing(4.52±0.12),Rotation,Visual recognition(8.34±0.62),Figure recognition(8.13±0.43),Visual recall(6.957±0.48),Association thinking(7.39±0.51),the touch memory(61.06±9.09),Recite(6.17±0.31) and Inverse recite(3.13±0.14),the trail making test B(122.39±8.28)(P<0.01). 2) Compare of cognition after left and right side basal ganglia's stroke:there were six items of cognition have significant difference,those were Digit symbol,Orientation,Executive complete number of categories (Cc),Executive error responsive number (Re),non Executive persist error number (nRpe),Executive persist number (Rp) (P<0.01). 3) Correlative analysis:direct and inverted recite negative correlated with stroke volume(r=-0.857,-0.811;P=0.014,0.027),Completed number of categories have positive correlation with stroke volume (r=0.822,P=0.023). The left side stroke correlated with Vocabulary Test,Experience,Visual recognition(r=-0.764,-0.907,-0.747;P=0.027,0.002,0.033); the right stroke correlated with Vocabulary Test,Symbolic figure,Visual renewable,negative correlation with Executive completed number of categories(r=-0.747,-0.770,-0.798;P=0.033,0.026,0.011).Conclusion Basal ganglia's stroke can cause various cognition disorders,especially in vocabulary intelligence,executive function and memory. The different side of basal ganglia's stroke may have different effect on procedure intelligence,long-term memory and executive function. Stroke volume related with cognition. Key words: Ischemic Stroke; Basal ganglia; Cognition