Abstract
A study on clinico-laboratory profile of newborns with perinatal asphyxia admitted to tertiary care hospital
Highlights
Asphyxia is the single most important cause of still-births accounting for 45.1% of all cases
Many organ systems can be affected by hypoxia-ischaemia, it is the nervous system that bears the brunt of perinatal asphyxia in the long
Distribution of Perinatal factors among the asphyxiated newborns- Among the study group, 51 (55.4%) neonates, mothers were Primigravida and 41 (44.6%) neonates’ mothers were multigravida. (16.3%) of the babies were born to PIH mothers, 3 (3.3%) were born to APH mothers and (17.4%) were born to anemic mothers
Summary
Asphyxia is the single most important cause of still-births accounting for 45.1% of all cases. Many organ systems can be affected by hypoxia, it is the nervous system that bears the brunt of perinatal asphyxia in the long run. The present study aims at correlating the Severity of asphyxia with the severity of HIE and to assess the perinatal factors, clinico laboratory profile and immediate outcome in asphyxiated newborns. Conclusion: In this study, there is a statistically significant association between severity of perinatal asphyxia and severity of HIE. Though the neonatal factors like male sex, SGA, LGA and perinatal factors like MSAF, PROM, maternal anemia, LSCS, instrumental delivery and breech presentation are associated with the outcome of HIE (sequelae/death), there is no statistically significant association. Many organ systems can be affected by hypoxia-ischaemia, it is the nervous system that bears the brunt of perinatal asphyxia in the long. Once the cerebral injury has occurred, the management is mainly supportive
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