A study on clinical characteristics and management of anaphylaxis in Emergency Department

Abstract

Objective: The aim of this study was to describe clinical features and outcome of patients with anaphylaxis at the Emergency Department - 108 Military Central Hospital in 2021. Subject and method: A cross-sectional, retrospective descriptive study of 146 anaphylaxis patients who came to Emergency Department - 108 Military Central Hospital in 2021. Result: Drug-induced anaphylaxis accounted for 65.8%, of which: Antibiotics accounted for 17.7%, vaccines accounted for 27.1%, contrast agents accounted for 10.4%. Common symptoms were: Mucocutaneous lesion (98.6%), respiratory (16.4%), digestive (6.8%), cardiovascular (4.8%), neurological disorders (2.1%). Anaphylaxis of grade I accounted for 76.7%, grade II accounted for 18.5%, grade III accounted for 4.8% and there was no anaphylaxis of grade IV. There was no statistically significant relationship between the degree of anaphylaxis and the entry of the allergen. The fluid transfusion counted for 100%, corticosteroid use (91.1%), dimedrol (84.2%), adrenaline (23.3%), oxygen therapy (13.7%) and invasive ventilation (0.7%). Conclusion: The main cause of anaphylaxis was drug-related, the most common symptom of anaphylaxis was manifestation of mucosal skin, the anaphylactic subjects were mainly grade I. Most of patients was complete recovery.