Abstract

BACKGROUND: Congenital heart disease (CHD) is one of the most common congenital malformations. Presence of cardiac murmur could be a warning sign of serious CHD. This study is done to emphasize the meticulous examination of the neonates for murmur and early referral for diagnosis and interventional therapy. OBJECTIVES: a. To determine the presence or absence of heart disease in neonates with cardiac murmurs. b. To identify clinical characteristics which differentiate pathological murmur from functional murmur. c. To assess the reliability of routine clinical neonatal evaluation in diagnosing CHD. d. Follow up of babies with detected lesion at 6 weeks of age to know about the evaluation of murmur. METHODOLOGY: Hospital based prospective study was conducted for a period of 12 months. All term neonates delivered in our hospital with cardiac murmurs were taken up for study. Detailed history was taken and associated clinical features noted. Chest X-ray and ECG were taken. Following which all neonates underwent echocardiography. Parents of babies with detected abnormality were counseled. These babies were followed up at 6 weeks of age for persistence of murmur and CHD. RESULTS: Among 4116 deliveries, 98 neonates with cardiac murmur were taken up for study. The percentage of having CHD among neonates with murmur was 53.06%. The incidence of heart disease in our hospital was 12.6%. VSD was the commonest defect. Incidence of CHD is higher in neonate of consanguineous parents. It is possible to make clinical diagnosis of murmur as innocent or pathological based on associated clinical features, X-ray and ECG abnormalities. CONCLUSION: It is important to evaluate all neonatal cardiac murmurs before they become symptomatic. Early diagnosis aids in early referral and appropriate intervention. These reduce morbidity and mortality . By evaluation of neonates based only on murmurs few CHD can be missed.

Highlights

  • Congenital heart disease is one of the most common congenital malformations

  • The total number of live births occurred during the study period was 4116 and among them 98 neonates were found to have murmur during auscultation and only those 98 neonates were included in our analysis

  • It is inferred from the table that as the grading of murmur increases the possibility of having congenital heart disease was found to be higher as there is a statistical significant association exist between the grading of murmur and the presence of CHD (p

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Summary

Introduction

Congenital heart disease is one of the most common congenital malformations. It remains the major cause of death in babies with congenital malformations. The most common presentations of the neonates with congenital heart disease are heart murmur, respiratory distress, cyanosis and congestive cardiac failure. They may have abnormal chest x-ray and ECG findings. The neonatal examination takes place at a time of rapid change within the cardiovascular system as part of adaptation to extra uterine life [7]. These changes may produce murmurs which can be mistaken for heart disease [8]. Conclusion: It is important to evaluate all neonatal cardiac murmurs with echocardiogram before they become symptomatic

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