Abstract
Transient hyperkalemia is well known to occur in man following intravenous administration of succinylcholine chloride. To study on change of the serum level of K+, Na+ & Cl- after injetion of succinylcholine in healthy adults, physical status 1 or 2 adopted by the American society of Anesthesiologists, we studied in two grcups: pentothal sodium-succinylcholine injetion group (group 1) as control, flaxedil-pentothal sodium-succinylcholine injetion group(group 2) as experimental. The following results were obtained: 1. Serum K+ was slightly increased in both groups, 2mEq/L at 3rd minute in control group, 2mEq/L at 1st minute in experimental group after succinylcholine injection, but no statistical significance was noticed in either group. 2. Serum Na+ was decreased 3mEq/L immediately after pentothal sodium injetion and then sliyhtly increased untill 10th minute in control group. In experimental group lower level than control was observed untill 15th minute, with the maximum decrease of 7mEq/L at 5th minute. But no statistical significance was noticed in either group. 3. Serum Cl was slightly decreased untill 10th minute with the maximum decrease of 4mEq/L at 5th minute in control group. In experimental group, it was slightly increased untill 5th minute. But no significance was noticed in either group.
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