A study on association between obstructive sleep apnea syndrome (OSAS) and epworth sleepiness score (ESS), physical and mental components related with quality of life (QOL)

Abstract

Introduction Obstructive sleep apnea syndrome (OSAS) put adverse impacts on the quality of life (QOL). Excessive sleepiness and other associated symptoms may negatively affect ability to learn, employment, and interpersonal relations, and directly degrade QOL. The objective of the present study was to evaluate the impact of OSAS on Epworth Sleepiness Score (ESS), Physical and Mental components related with QOL. Materials and methods Design : Observational, Hospital based study Setting: Study was carried out in 190 index subjects in polysomnography unit of Department of Pulmonary Medicine, KGMU, India. Method : Overnight sleep study was carried out in all subjects on polysomnography unit. Hindi version of HRQOL tool SF-36 was used to evaluate Physical Functioning (PF), Role Physical (RP), Bodily Pain (BP), General Health (GH), Vitality (VT), Social Functioning (SF), Role Emotional (RE), Mental Health (MH), Physical Component Summary (PCS) and Mental Component Summary (MCS) in these subjects. Results PCS was found to be associated with BMI, Neck Circumference, Blood Pressure, Hypopnea, and number of total Desaturation fall events below 5% while MCS was found to be associated with BMI and Hypopnea events in these subjects. In males, severity of disease was found associated with BP, RP and MCS ( p = 0.05, 0.03 and 0.01 respectively) whereas in females, severity of disease was significant association with parameters such as BP ( p = 0.02), GH ( p = 0.01), VT ( p = 0.01), SF ( p = 0.02), PF ( p = 0.04), RP ( p = 0.001) and PCS ( p = 0.000). Conclusion Physical Component Summary (PCS) and Mental Component Summary (MCS) are related with sleep related events in these subjects thus improvement in these parameters through various treatment modalities can be used to improve QOL in this population. Acknowledgements I would like to thank my guide and my co-guides who help me to walk in a right direction. I would also like to thank all the subjects who respond me so patiently. I would also like to thank to God for being with me throughout my work.