Abstract

Introduction: Paracetamol acts by the inhibition of Cyclooxygenase (COX) mediated production of Prostaglandin unlike the non steroidal anti inflammatory agents, so it was found that tissue inflammation was not reduced. Methodology: A detailed pre-anaesthetic checkup carried out in each patient. Patient is kept nil per orally 6 hours prior to surgery, i.v line secured, pre medicated with Inj Ranitidine 50mg iv, Inj Ondansetron 4mg iv and IVF Ringer Lactate infusion at 100ml/hr 3 hours prior to surgery. Results: Among the patients undergoing spinal anaesthesia in fracture femur surgery, there was no statistically significant difference in Blood pressure, Mean arterial pressure (MAP) between the groups. Conclusion: Among the patients undergoing spinal anaesthesia in fracture femur surgery, there was no statistically significant difference in Oxygen saturation (SpO2) between the groups

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