Abstract
Sodium bisulphite (NaHSO 3) at low concentrations is known to undergo radical reactions in the presence of Mn 2+ ions, generating sulphite anion radicals (SO 3 − ·). The kinetics of pH variation in aqueous solutions of NaHSO 3 in the presence of 0.1 mM-MnSO 4 suggests that the anion radicals are generated rapidly at low bisulphite concentration (10 mM) and quenched at a higher concentration (100 mM). The ability of NaHSO 3 to induce gene conversion in the diploid yeast Saccharomyces cerevisiae BZ34 under conditions suitable for radical reactions has been investigated. The results show that NaHSO 3 does not induce gene conversion under these conditions.
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