Abstract
1. The levels of hepatic microsomal monooxygenase in sea birds were determined using organochlorine substrates. Levels of cytochrome P 450 and organochlorine residues were also measured. 2. The razorbill ( Alca torda) and puffin ( Fratercula arctica) showed highly variable activities which were resolved into multiple peaks on frequency diagrams. 3. The most active individuals amongst razorbills were early season females with large ovaries. Otherwise no relationship was found between activity and sex, site, time of year or PCB residues. 4. The properties of monooxygenase from individuals of low and high activity were compared. 5. The results are discussed in relation to PCB pollution.
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