A study of the fluctuation in immunoglobuline E (IgE) in tonsillogenic focal diseases (author's transl)

Abstract

In 35 cases with tonsillogenic focal diseases, IgE levels in tonsillar tissues and serum were evaluated at pre- and post-operative stages by means of radio-immuno-sorhent method. The results obtained were as follows; (1 ) The tonsillar IgE level was slightly higher in chronic nephritis and lower in slight fever and rheumatoid arthritis, while the serum IgE level increased in rheumatic fever and decreased in Pustulosis palmaris et plantaris both at pre- and post-operative stages. (2) The tonsillar IgE level was higher in the group showing positive result in provocation test, while the serum IgE level increased in the positive group and slightly decreased in the negative, both at pre- and post-operative stages. (3 ) With regard to the effect of tonsillectomy on focal diseases, the tonsillar IgE level was slightly higher in cured group and lower in improved group, while the serum IgE level slightly decreased in the improved, both at pre- and post-operative stages. (4) Two patients of acute nephritis and chronic nephritis with markedly high (over 1000 U/ml) tonsillar IgE were completely cured after tonsillectomy. However, only 12 out of 22 patients with markedly low (under 100 U/ml) tonsillar IgE level recovered after tonsillectomy. (5 ) Clinical observations on 30 patients for over one year after tonsillectomy revealed that 18 were recovered, 11 improved and one was not improved. The result would indicate that tonsillectomy was effective for tonsillogenic focal diseases in 96. 7% of the cases investigated.