Abstract
Introduction: Permanent scars are the major complications of acne. Correction of scars is the priority for acne patients. Platelet-rich plasma (PRP) may be useful in the treatment of atrophic acne scars by promoting collagen deposition. Skin needling also releases growth factors, initiate a cascade of wound healing resulting in collagen production. Hence, skin needling and PRP should act synergistically to improve acne scars.Objective: To assess the effectiveness of the combined use of skin needling and PRP application in acne scar treatment.Material and Methods: The study enrolled 10 patients of acne scars. Platelet rich plasma therapy with needling was given to them at monthly interval for a therapeutic period of 6 months. The effects of therapy were evaluated based on photographic assessment and patient’s satisfaction.Results: Mean age of the patients was 28.10 ± 5.065. Twenty percent of patients showed excellent response, 80% showed good response. The results were found to be significant with p value < 0.014. Pain and edema were major complaints which subsided in 1-2 days.Conclusion: Platelet rich plasma therapy combined with skin needling is a safe and effective treatment for management of acne scars.
Highlights
Permanent scars are the major complications of acne
Platelet rich plasma therapy combined with skin needling is a safe and effective treatment for management of acne scars
Many techniques are available for the correc on of atrophic acne scars, including subcision, dermabrasion, chemical peeling, laser technology, fat gra ing, and use of fillers; these techniques have resulted in varying degrees of success and associated adverse effects.[5,6,7,8]
Summary
Permanent scars are the major complications of acne. Correction of scars is the priority for acne patients. Atrophic acne scars are by far the most common type.[4] Facial scars lead to cosme c problems, and have psychological effects such as emo onal debilita on, embarrassment, poor self-esteem, and social isola on.[5] Many techniques are available for the correc on of atrophic acne scars, including subcision, dermabrasion, chemical peeling, laser technology, fat gra ing, and use of fillers; these techniques have resulted in varying degrees of success and associated adverse effects.[5,6,7,8] It has been postulated that autologous platelet-rich plasma (PRP) could be used for the treatment of atrophic facial scars, because it can enhance wound healing, which has been shown to accelerate ssue repair.[5,9] Percutaneous collagen induc on or skin needling has recently been proposed as a simple and effec ve therapeu c op on for the management of atrophic scars.[10] Skin needling is a technique that uses a sterile dermaroller to puncture the skin and release growth factors. This current study was conducted aiming to clarify the efficacy and safety of each modality
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