A Study of the acupuncture point embedding therapy on slow transit constipation along with colon transmission function,plasma SP and VIP

Abstract

Objective To explore the clinical efficacy of acupuncture point embedding therapy in the treatment of slow transit constipation （STC）and the influence on the colon transmission function,plasma substance P（SP）, vasoactive intestinal peptide（VIP）. Methods A total of 128 slow transit constipation patients were involved in the study and divided randomly into two groups by using stochastic indicator： a treatment group （treated with acupuncture point embedding therapy） and a control group （treated with lactulose oral liquid）. The clinical effects, colon transmission function, the influence of SP, and VIP were observed for STC patients. Results In the treatment group, CCS score was （13.52±3.93） before treatment and（8.15±3.77） after the treatment. In the control group CCS score was （14.11±4.24） and （9.01±2.93） respectively before and after the treatment, CCS score in both groups showed significantly improvement after the treatment （P〈0.01）, and there was no significant difference between groups （P〉0.05）. The plasma SP and VIP level of the two groups after the treatment [treatment group （46.73±1.50） ng/L,（206.10±12.14） ng/L, the control group（40.92±6.25）ng/L,（214.73± 7.62）ng/L] were also improved than before [treatment group was（26.66±0.88）ng/L, （332.68±17.84）ng/L, the control group was （23.32±1.75）ng/L,（306.22±20.01）ng/L], with statistically significant（P〈0.05）, and the difference between the two groups were also significant（P〈0.05）.Conclusion The acupuncture point embedding therapy is effective for STC, and it can regulate the level of SP and VIP. Key words: Acupuncture point embedding therapy; Slow transit constipation; Colon transmission function; SP; VIP