Abstract

Objective To investigate the sleep architecture in dementia with Lewy bodies (DLB), and study the sleep architecture and cognitive functions in DLB. Methods We described polysomnography (PSG) findings in 34 consecutive subjects diagnosed with DLB. All the patients underwent Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Clinical Dementia Rating (CDR) to quantify cognitive functions. Results ⑴Sleep architecture analysis: DLB group compared to normal control group, the sleep period time (SPT) was reduced (P 0.05). Conclusions Patients with DLB exists sleep architecture disorder. The cognitive functions and sleep architecture changes in patients with DLB have no obvious correlation. It is different from other degenerative dementia. Key words: Lewy body disease/PP; Sleep; Cognition

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