Abstract

Sexually transmitted infections is most common infectious disease for public health. Human immunodeficiency virus (HIV) alters the clinical presentation of sexually transmitted infections, their natural history, relative prevalence and response to treatment. To study the sexually transmitted infections and their correlation with the CD4 T cell counts among HIV – infected patients. Department of dermatology, venereology and leprology, tertiary care hospital, Cross-sectional study. A total of one hundred and fifty-five cases of HIV seropositivity were studied over a period of twelve months. A detailed history covering all relevant points was recorded in all cases. Each patient underwent a thorough general, physical, systemic, dermatological and venereological examination. Twenty-five out of one hundred fifty-five cases had sexually transmitted infections. All relevant investigations were done and data was recorded.Statistical analysis used: Data analysis was done using Statistical Package for Social Sciences (SPSS) v.21 for windows and Chi-square test was used. Out of the twenty-five patients, nineteen were males, five females and one transgender. Maximum numbers of patients were between the age group of 31-40 years. Most common sexually transmitted infection was herpes progenitalis (64%). Others were genital warts (16%), balanoposthtitis (8%), gonorrhea (4%), syphilis (4%), buschke-lowenstein tumour (4%) and genital molluscum contagiosum (4%). There is a strong association between the occurrence of HIV and the presence of sexually transmitted infections. Both HIV and sexually transmitted diseases are closely interlinked. So, early diagnosis, treatment and control of sexually transmitted diseases offer a rational approach to the management.

Highlights

  • The objective of the present study is to find out association of Human immunodeficiency virus (HIV) infection with various sexually transmitted infections and correlate with their CD4 T cell counts

  • The highest incidence of HIV positive patients is in the age group of 21-40 years (65.16%) which highlights the fact that it is most common in sexually active age group which makes them most vulnerable similar results were reported in other studies. 4–9 Maximum patients were from a rural background and mainly were illiterate

  • The most common type of Sexually Transmitted infection in the present study was Herpes progenitalis with a mean CD4 T cell count of 289.81 cells/cumm which was almost similar to 239.00 cells/cumm in a study done by Vasudevan et al and higher than 198 cells/cumm in Bosamiya et al study and 187 cells/cumm in Shobhana et al study, 11,12 similar results were reported in other studies. 13–16 It was the most common STD found in all the related studies except Nair et al 7 study where syphilis

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Summary

Introduction

The objective of the present study is to find out association of HIV infection with various sexually transmitted infections and correlate with their CD4 T cell counts. STDs have remained a health issue since many centuries; they became a major health problem worldwide by the appearance of HIV around 1980. The relationship between sexually transmitted infections and HIV is complex. They facilitate transmission of HIV by increasing the infectiousness and susceptibility of the partner. 1,2 In turn; HIV infection alters the natural history, manifestations and treatment of sexually transmitted infections They facilitate transmission of HIV by increasing the infectiousness and susceptibility of the partner. 1,2 In turn; HIV infection alters the natural history, manifestations and treatment of sexually transmitted infections

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