Abstract

Enteric fever, Dengue and malaria still remain diseases of public health importance in the tropics. The aim of the study to see the serodiagnostic challenges in enteric fever cases presenting as co-infection with dengue and malaria. The cross sectional study was conducted in the department of Medicine and Department of Microbiology, Holy Family Red Crescent Medical College Hospital, from July 2016 to June 2017. Febrile patients attending the outpatient department or admitted to hospitals attached to Holy Family Red Crescent Medical College Hospital suspected to have signs and symptoms clinically suggestive of typhoid, malaria and/or dengue were initially enrolled. Seropositivity of typhoid-dengue it was observed that 55 (55.0%) patients had dengue IgM+typhoid, 27 (27.0%) had dengue IgG+typhoid, 10(10.0%) had dengue IgM+IgG+typhoid and 08(8.0%) were negative. Seropositivity of typhoid-malaria of the patients, it was observed that p. falciparum+typhoid was found in 33 (33.0%), p. vivax+typhoid was 22 (22.0%) and negative was 45 (45.0%). Male patients while co-infection with typhoid fever observed more than in female population. In the present study Seropositivity of typhoid-dengue fever is high of co-infections are common than typhoid-malaria, hence it should be properly diagnosed and timely medication should be provided to reduce complications and get proper treatment.

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