A Study of Response Inhibition in Overweight/Obesity People Based on Event-Related Potential.

Ze-Nan Liu,Dai-Lin Zhang,Jing-Yi Jiang,Tai-Sheng Cai

doi:10.3389/fpsyg.2022.826648

Ze-Nan Liu, Dai-Lin Zhang + Show 2 more

Open Access

https://doi.org/10.3389/fpsyg.2022.826648

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Abstract

ObjectiveTo investigate the characteristics of response inhibition of overweight/obese people, using behavior experiments combine with neural electrophysiological technology and discussing the difference in impulse level between obesity/overweight and normal-weight people through EEG data, questionnaire, and behavior experiment.Method(1) All participants completed the Go/Nogo task; meanwhile, behavior data and 64 channel EEG data were recorded. (2) Participants completed the Stop-Signal task and behavior date was recorded.Results(1) During Go/Nogo task, no significant differences were found in reaction time, omission errors of the Go task between the two groups, while commission errors of the Nogo task of the control group were significantly greater than the overweight/obesity group. (2) About SSRT during the Stop-Signal Task, the interaction of stimulus type (high-calorie food picture, low-calorie food picture) and group (control group, overweight/obesity group) was significant (p = 0.008). (3) No significant differences were found between the two groups in amplitude and latency of N2. About the amplitude of P3, the interaction of task type (Go task, Nogo task), electrode point (Cz, CPz, Pz), and groups were significant (p = 0.041), the control group P3 amplitude was significantly greater than overweight/obesity group during the Nogo task. Regarding about latency of P3, the interaction of group and electrode point were not significant (p = 0.582), but the main effect of task type was significant (p = 0.002).Conclusion(1) In terms of behavioral outcomes, overweight–obese subjects had lower dominant response inhibition and response cessation compared to normal-weight subjects. (2) In terms of EEG results, overweight–obese subjects showed no difference in processing speed and level of conflict monitoring for early inhibitory processing compared to normal-weight subjects, but there was a deficit in behavioral control for late inhibitory processing.

Highlights

Obesity/overweight is a chronic disease caused by excessive energy intake by the body, resulting in the accumulation of fat or excessive weight beyond the normal range
In terms of EEG results, overweight/obese subjects showed no difference in processing speed and level of conflict monitoring for early inhibitory processing compared to normal-weight subjects, but deficits in behavioral control for late inhibitory processing. Both of these findings suggest that there are some problems with response inhibition in overweight/obese subjects, contributing to our understanding of the causes of simple obesity while adding to the theoretical basis for response inhibition in the obese population
The study findings provide empirical information for intervention and treatment of overweight obesity, suggesting that the general public should pay attention to the functional impairment produced by overweight obesity in individuals and strengthen the importance of obesity in society

Summary

Introduction

Obesity/overweight is a chronic disease caused by excessive energy intake by the body, resulting in the accumulation of fat or excessive weight beyond the normal range. Overweight/obese individuals are significantly impaired in executive function. Executive function is a complex system in which individuals coordinate multiple cognitive subcomponents during the completion of goal-directed behaviors, mainly including working memory, cognitive switching, and inhibitory control (Smith and Jonides, 1999). Inhibitory control, called self-control, is a central component of executive function It can reflect inhibition at the behavioral level and is the control of an individual’s exercise over their attention, behavior, thoughts, and emotion (Smith and Jonides, 1999; Zelazo and Carlson, 2012; Diamond, 2013). For obese or overweight individuals, deficits in response inhibition are mainly manifested by the inability to suppress cravings for high-calorie foods and frequent failures in the execution of weight loss plans (Blume et al, 2018). It has been shown that obese adolescent girls have significantly lower response inhibition to food than normal-weight girls of the same age (Batterink et al, 2010)

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