Abstract
The study aims to determine the association of nonalcoholic fatty liver disease in metabolic syndrome patients to find out the prevalence of nonalcoholic fatty liver disease in the already diagnosed metabolic syndrome patients selected from the South Indian population. Find out the correlation and general characteristics of nonalcoholic fatty liver disease in patients with metabolic syndrome. To determine the potential risk factors for developing steatohepatitis in nonalcoholic fatty liver disease cases with metabolic syndrome and establish the risk categories for developing steatohepatitis in these patients. There is an increased prevalence of all the factors of metabolic syndrome and changes are seen in biochemical markers in nonalcoholic fatty liver cases.
Highlights
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases affecting a large number of people
These patients were selected based on the criteria for metabolic syndrome as established by National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III), JAMA [8]
Metabolic syndrome has become one of the more prevalent diseases in Asian countries and with an increased incidence of obesity and insulin resistance especially among the Indian population, we have found a rise in NAFLD due to metabolic syndrome excluding other causes
Summary
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases affecting a large number of people. NAFLD denotes liver with excessive fat accumulation and occurs insignificant proportion of people who do not consume alcohol. It ranges from simple steatosis to steatohepatitis, advanced fibrosis. Studies have shown its progression to cirrhosis and even hepatocellular cancer. NAFLD is strongly related to metabolic syndrome. Obesity, and metabolic syndrome are considered some of the risk factors for NAFLD [1,2,3]
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