Abstract
The use of mobile communication devices in health care is spreading worldwide. A huge amount of health data collected by these devices (mobile health data) is nowadays available. Mobile health data may allow for real-time monitoring of patients and delivering ad-hoc treatment recommendations. This paper aims at showing how this may be done by exploiting the potentialities of fuzzy clustering techniques. In fact, such techniques can be fruitfully applied to mobile health data in order to identify clusters of patients for diagnostic classification and cluster-specific therapies. However, since mobile health data are full of noise, fuzzy clustering methods cannot be directly applied to mobile health data. Such data must be denoised prior to analyzing them. When longitudinal mobile health data are available, functional data analysis represents a powerful tool for filtering out the noise in the data. Fuzzy clustering methods for functional data can then be used to determine groups of patients. In this work we develop a fuzzy clustering method, based on the concept of medoid, for functional data and we apply it to longitudinal mHealth data on daily symptoms and consumptions of anti-symptomatic drugs collected by two sets of patients in Berlin (Germany) and Ascoli Piceno (Italy) suffering from allergic rhinoconjunctivitis. The studies showed that clusters of patients with similar changes in symptoms were identified opening the possibility of precision medicine.
Highlights
Mobile Health refers to the use of mobile communication devices in health care
The results of the two above-mentioned studies involving the application of the FkMedFD algorithm are reported
The first step of the analysis was the computation of daily Symptom Medication Scores (SMS) values on the basis of the daily Mobile Health (mHealth) data recorded by AllergyMonitor
Summary
Mobile Health (mHealth) refers to the use of mobile communication devices in health care (see, e.g., [1]). Nearly every person possesses a mobile device and people carry their mobile device with them wherever they go. A study of longitudinal mobile health data through fuzzy clustering methods for functional data (Technology Projects & Software) Production srl. No further financial support was given by TPS to this study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript
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