Abstract

Lichen planus (LP) is a disease which affects stratied squamous epithelia of the skin or mucus membrane, this is a T-cell mediated disease. LP generally involves the skin or mucous membranes including the oral, esophageal, vulvovaginal, conjunctival and laryngeal mucosa. Several drugs, typically anti-hypertensive medication or infections, particularly viral hepatitis can be responsible for inducing LP. The current rst-line treatment includes topical and/or systemic corticosteroids. In addition, immune-suppressants can also be used as corticosteroid sparing agents. Anyone can develop LP but middle-aged adults are affected most often whereas Oral Lichen Planus (OLP) most often affects middle-aged women. Here two case reports have been discussed focusing Lichen Planus of both skin and mouth. The case reports also provide the information regarding physical examination of the patients, results of their histological ndings and other pathological tests (Biopsy, Haematology, Complete Blood Count, Liver Function Tests, Plasma Glucose, etc.) and their thorough treatment plan with its outcome. Both the cases showed improvement from the treatment provided for this autoimmune disorder and we can expect a permanent cure of this disease in times to come.

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