Abstract
The ion-pair formation between erythromycin (E) and bromothymol blue (BTB), methylthymol blue (MTB), and thymol blue (TB) has been studied spectrophotometrically. The three dyes have been found to form ion-pair associates with E in acid and neutral solutions. The optimal pH values being 2.8, ca. 4, and ca. 4 for the associates with BTB, MTB, and TB, respectively. The associates were extractable with chloroform and exhibited absorption maxima at 415, 430, and 550 nm, respectively. The composition of the associates was established by Job's method and by spectrophotometric titration. The ion-pair associates E-BTB and E-MTB were subsequently utilized for assaying erythromycin in two dosage forms.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
