Abstract
A model for the proerythroblast compartment of the rat erythroid system has been presented, based upon the assumption that cells divide at all points in the compartment. On the basis of this model an equation has been formulated, relating the 55Fe labelling index with time after injection of 55Fe. The experimental results have been analysed with the help of this equation, and give the following estimates for the parameters defining the cell kinetics of the compartment: a fractional inflow ( f N ) of 0.011/hr; a fractional outflow ( F N ) of 0.08/hr; a compartment transit time of 28.5 hr; a mean of 2.9 divisions as a cell passes through the compartment; and a mean cell cycle time of 9.8 hr. In addition it has been shown that cells make roughly seven divisions during their lives as recognised erythroid precursors.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
