A Study of Correlation of C-reactive Protein, and Physical and Metabolic Indicators of Cardiovascular Risk in Menopausal Transition

Abstract

The metabolic changes accompanying menopauseare all established risk factors for cardiovascular morbidity. These factors are known to act in conjunction with each other, and inflammation is possibly a common mechanism which is responsible for atherogenesis. C-Reactive Protein (CRP) has been found by several workers to be a reliable marker of pro-inflammatory state and is also a predictor of cardiovascular risk. So CRP level estimation may add to predictive capacity in cardiovascular risk assessment. This study attempts to explore the physical and metabolic changes in post-menopausal women and to explore whether these parameters show significant correlation with CRP levels. If so, then CRP estimation can be used as a tool to assess cardiovascular risk in post-menopausal women.