Abstract
The stability of AHF in fresh frozen plasma stored at −30 C. was found to be the same for plasma stored in glass containers, silicone‐coated or plastic containers. Less than 24 per cent of the original AHF was lost during storage for periods up to 126 days. Shaking the plasma during thawing was shown to have a deleterious effect on the AHF activity. The rate of loss of AHF activity from plasma kept at room temperature after thawing was rapid, regardless of the nature of the storage vessel.In vivo experiments demonstrated good correlation between AHF levels in fresh frozen plasma and the actual rise in AHF activity of a patient with severe hemophilia.
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