Abstract
205 Background: Intractable ascites associated with cancerous ascites causes severe abdominal distention, loss of appetite, poor nutritional condition and reduce the quality of life. We treat patients suffering from cancerous ascites by Cell-free and Concentrated Ascites Reinfusion Therapy (CART). But, cancerous ascites contains a lot of cellular components, and it easily cause filter obstruction. So we applied new method of CART: KM-CART in cancerous ascites patients. This CART system has a filter cleaning function, so the system has less incidence of filter obstruction. We report on our experience on CART for patients with cancerous ascites. Methods: Since November 2009 to August 2014, we applied CART in 31 cases of cancerous ascites (gastric cancer, 13; colorectal cancer, 6; pancreatic cancer, 10; others, 2). Results: On average, 3.8kg (range 1.2-7.5kg) of ascites were filtrated and concentrated to 440g (70-1110g). In all cases abdominal distention disappeared and abdominal girth decreased. Side effect was only mild fever on 11 cases. Conclusions: CART is safe and effective treatment for patients with cancerous ascites. This treatment may be able to improve quality of life with peritoneal dissemination.
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