Abstract
Results Out of 100 HIV infected children, 42% [25 males, 17 females] had cardiac abnormalities of which only 6 [14%] were symptomatic. Majority belonged to WHO clinical stage IV, with 13 [28%] having low CD4 count. The most common cardiac abnormality was left ventricular systolic dysfunction (LVSD) in 19% (p 0.05). Conclusion Though the majority of the children were asymptomatic, investigations revealed 42% with subclinical cardiac abnormalities. They had significant dyslipidemia and anemia as compared to children without cardiac abnormalities. The study thus emphasizes the need for routine echocardiographic screening.
Highlights
Studies have demonstrated the presence of abnormality on echocardiography in HIV infected adults, but there is a paucity of similar data regarding children in the Indian subcontinent
Background Studies have demonstrated the presence of abnormality on echocardiography
The objectives of this study were to evaluate the cardiac abnormalities in HIV infected children
Summary
Studies have demonstrated the presence of abnormality on echocardiography in HIV infected adults, but there is a paucity of similar data regarding children in the Indian subcontinent. The objectives of this study were to evaluate the cardiac abnormalities in HIV infected children and to know the metabolic and nutritional risk factors for cardiac disease
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