A study of association of various clinicopathological factors in seroma formation after mastectomy in carcinoma breast

Abstract

Introduction: Breast Cancer is the most common site specific cancer in women and is the leading cause of death from cancer for women aged 20-59 yrs. Surgery has the major role in the management of Carcinoma Breast. Among all, seroma, a subcutaneous collection of serous fluid is a common complication after mastectomy. However excessive accumulation will stretch the skin resulting in patient discomfort and prolongation of hospital stay.). In this study, we carried out a systematic review of risk factors for seroma formation and its association with various clinical pathological and technical parameters with seroma formation. Study has further tried to discuss treatment of seroma formation. Aims and Objectives: To evaluate influence of clinical, pathological & technical parameters in relation to seroma formation and effectiveness of various modalities in treatment of seroma formation. Material and Methods: In the Department of General Surgery, VIMSAR, Burla, from July 2018 to June 2020, 50 numbers of female patients with carcinoma breast undergoing mastectomy after taking informed consent are followed post operatively and association of seroma formation with various clinicopathological factors namely Age, obesity and co morbidities, Stage, size, type and grade of tumor, lymph node involvement, Type of surgery, Neo-adjuvant and Adjuvant chemotherapy, Adjuvant radiotherapy, use of electro cautery, application of compression bandage are evaluated along with effectiveness of various modalities in treatment of seroma formation.Result: Seroma formation occurs in 20% of cases and is not associated with Age of patient or presence of obesity and co morbidities or Stage, size, type and grade of tumor or lymph node involvement or Type of surgery or Neo-adjuvant and Adjuvant chemotherapy or Adjuvant radiotherapy(p>0.05). Electrocautery is significantly associated (p