A study of A2B subgroup frequency among AB blood group in our tertiary care center

Abstract

Background: The ABO blood group system invented by Karl Landstiner is popular blood grouping system and considered as the most vitalin blood transfusion safety. Approximately, 20% of individuals having A2 subgroup and 80% have A1 subgroup. Aims and Objectives: The objective of the present study is to find the prevalence of A1B and A2B subgroups in samples of patients in blood center of our tertiary care center. Materials and Methods: This observational study was carried out at blood center of tertiary care hospital. Blood group is separated into A, B, AB, and O-positive/negative. Based on serological reactivity, blood group was classified into A2B positive/A2B negative. Results: ABO blood grouping was analyzed for 5435 samples. Of these, 430 (7.91%) belonged to Group AB. Out of 430 AB group, 13 (3.1%) were having A2B-positive blood group and 417 (96.9%) were having A1B-positive blood group. Conclusion: Among AB blood group, frequency of A1B subgroup is higher than A2B. The study of this subgrouping can make blood transfusion more safe and can improve overall practice of transfusion.