Abstract

WE HERE DESCRIBE A PROGRESSIVE step-wise change in the thyroid weight of young White Carneau pigeons studied during 5 years, and also a marked difference in the responsiveness of the thyroids of White Leghorn baby chicks which were obtained from two sources and which probably represent two hereditary strains. Since increase in the weight of the thyroid gland of various animals has become an accepted quantitative method for measurement of the thyrotropic content of anterior pituitary extracts the observations bear upon a common problem. These two types of thyroid variability indicate that quantitative assays of thyrotropin require the use of parallel tests with a standard preparation of thyrotropin.Col,lip has reviewed the earlier studies on thyrotropin (1). Smelser (2), Kabak and Liapin (3), Cope (4) and Bergman and Turner (5) have used both baby chicks andguinea pigs for thyrotropin assays.

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