Abstract

Production of glucose and urea by livers of hypophysectomized rats was twice that by livers of normal rats when both were perfused with medium containing amino acids at either one or ten times their normal plasma concentrations. This suggested a stimulated rate of gluconeogenesis in the livers of hypophysectomized rats. Increased rates of conversion of 14C-alanine and 14C-lactate to glucose were observed in livers of these rats.

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