Abstract
A statistical shape-constrained reconstruction (SSCR) framework is presented to incorporate the statistical prior information of human lung shapes for lung electrical impedance tomography. The prior information is extracted from 8000 chest-computed tomography scans across 800 patients. The reconstruction framework is implemented with two approaches-a one-step SSCR and an iterative SSCR in lung imaging. The one-step SSCR provides fast and high accurate reconstructions of healthy lungs, whereas the iterative SSCR allows to simultaneously estimate the pre-injured lung and the injury lung part. The approaches are evaluated with the simulated examples of thorax imaging and also with the experimental data from a laboratory setting, with difference imaging considered in both the approaches. It is demonstrated that the accuracy of lung shape reconstruction is significantly improved. In addition, the proposed approaches are proved to be robust against measurement noise, modeling error caused by inaccurately known domain boundary, and the selection of the regularization parameters.
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