A statistical analysis and cytohistologic correlation of fine needle aspiration cytology in lesions of male breast

Abstract

Background and Objectives: Fine needle aspiration cytology is a widely used first line investigation for breast lesions in surgical practice. Gynecomastia is the most common lesion of male breast. FNAC is usually asked for male breast lesions in case of unilateral breast enlargement to rule out malignancy. This study was done to obtain sensitivity, specificity, other statistical parameters and cytohistological correlation in FNAC of male breast lesions so as to know its diagnostic utility. Methods: Study was performed at Goa medical college over a period of seven years. Only the cases with availability of histological diagnosis were included in the study. All slides were stained with Hematoxylin and eosin after fixation in alcohol-ether mixture. Results: Sensitivity, specificity, accuracy, positive predictive value and negative predictive value were 100% for FNAC of male breast lesions. Excellent cytohistologic correlation was also observed. Conclusion: These results indicate that FNAC of male breast lesions shows excellent specificity, sensitivity and cytohistologic correlation. Hence, it can be used in initial diagnostic workup of lesions of male breast. Keywords: Fine needle aspiration cytology, Male Breast lesions, Statistical analysis