Abstract
A study of the effect of various concentrations of sorbitol and temperature on the solubility and heat of solution of boric acid in water has been made. This system was studied at temperatures of 21°, 25°, 30°, 40°, 50°, and 60°. Concentrations of sorbitol ranging from 0 to 70 per cent by weight sorbitollin increments of 5 per cent were utilized in this study. The results of these experiments showed the relationship between (1) solubility of boric acid and (2) temperature and concentration of sorbitol. A phase diagram of the boric acid-water-sorbitol system is given. The heat of solution for the various systems was calculated. The specific gravity of all solutions was determined by the pycnometric method.
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More From: Journal of Pharmaceutical Sciences (Scientific Edition)
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