Abstract
One of the most serious adverse effects of radiotherapy is the induction of neoplasia in the tissues subjected to treatment. In spite of the very wide use of radiotherapy in the treatment of malignant disease, such induced neoplasms are not common and soft tissue sarcomas are rare (Gane et al., 1970; Jones 1953; Seydel 1975). We report a case of fibrosarcoma arising in the radiation field four years after successful radiotherapy for bronchial carcinoma. In February 1970 the patient, a 50-year-old male, complained of dyspnoea and pain in the chest after an attack of influenza. He had smoked 15 cigarettes a day for 35 years, but otherwise his past history was unremarkable. A chest X ray in April 1970 showed evidence of emphysema and irregular shadowing in the right hilar region, and sputum cytology revealed atypical squamous cells. Bronchoscopy snowed narrowing of the right main bronchus near its origin and a keratinising squamous cell carcinoma was found at biopsy.
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