Abstract

There are no ideal means for the diagnosis of intestinal bleeding diseases as of now, particularly in the small intestine. This study investigated an intelligent intestinal bleeding detection capsule system based on color recognition. After the capsule is swallowed, the bleeding detection module (containing a color-sensitive adsorptive film that changes color when absorbing intestinal juice,) is used to identify intestinal bleeding features. A hue-saturation-light color space method can be applied to detect bleeding according to the range of H and S values of the film color. Once bleeding features are recognized, a wireless transmission module is activated immediately to send an alarm signal to the outside; an in vitro module receives the signal and sends an alarm. The average power consumption of the entire capsule system is estimated to be about 2.1mW. Owing to its simplicity, reliability, and effectiveness, this system represents a new approach to the clinical diagnosis of intestinal bleeding diseases.

Highlights

  • Gastrointestinal (GI) hemorrhagic disease is a common clinical symptom [1,2,3,4], especially in the elderly patients

  • Capsule endoscopy represents a revolutionary breakthrough in noninvasive diagnosis of intestinal bleeding diseases [15]

  • This study proposes an intelligent intestinal bleeding detection capsule (IBDC) system based on color recognition of hue-saturation-light (HSL) color space in effort to ameliorate these problems in intestinal bleeding disease diagnosis

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Summary

Introduction

Gastrointestinal (GI) hemorrhagic disease is a common clinical symptom [1,2,3,4], especially in the elderly patients. Routine diagnosis methods for intestinal bleeding diseases, such as radionuclide scanning [7], digital subtraction angiography [8, 9], and endoscopic examination [10,11,12], generally are invasive or have substantial side effects, making physicians unlikely to administer them and patients unlikely to accept them [13, 14]. Capsule endoscopy represents a revolutionary breakthrough in noninvasive diagnosis of intestinal bleeding diseases [15]. Though the method is effective, there is sizeable burden placed on the physician–a rather excessive amount of image information (about 60000 images) [17, 18] must be scanned to identify bleeding lesion areas, and visual fatigue caused by long work hours may lead to PLOS ONE | DOI:10.1371/journal.pone.0166488. Though the method is effective, there is sizeable burden placed on the physician–a rather excessive amount of image information (about 60000 images) [17, 18] must be scanned to identify bleeding lesion areas, and visual fatigue caused by long work hours may lead to PLOS ONE | DOI:10.1371/journal.pone.0166488 November 30, 2016

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