A single-centre experience of 200 laparoscopic liver resections

Abstract

Objective To summarize the clinical experience of laparoscopic liver resection (LLR) for liver benign and malignant tumors. Methods Retrospective analysis was performed to review the pooled data of 200 patients treated with laparoscopic liver resection from Qilu Hospital between June 2012 and November 2015. These patients were assigned into left liver group (n=108) and right liver group (n=86) by tumor sites. The clinical data obtained from the two groups was compared in the aspect of patients' general information, surgical indicators and postoperative blood workup. Results There was no significant difference in the clinical data between the two groups. The operation duration and post-operative hospitalized days in the group R were significantly longer than those in the group L [(165.5±61.2) min vs. (135.6±62.5) min, P<0.05 for operative duration; (11.3±4.3)d vs. (9.4±4.8)d, P<0.05 for post-operative hospitalized days]. Blood loss in the group R was significantly more than that in the group L[(299.0±352.9)ml vs. (144.3±160.0)ml, P<0.05]. Hepatic vascular inflow occlusion was more frequently used in laparoscopic right liver resection, the average duration of this procedure was (24.5±7.3) min. The levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) elevated on day 1 and day 3 after LLR in both groups, with significant differences observed between the two groups. There was no statistical difference in prothrombin time (PT) of patients between the two groups. Conclusions This study suggests that laparoscopic liver resection is safe and effective in the management of liver neoplams. Compared with left liver group, the right liver group has been associated with inferior clinical outcomes of surgery complexity, operation duration, blood loss, postoperative hospitalization days, hepatic vascular inflow occlusion, and postoperative ALT and AST levels. Key words: Laparoscopy; Liver resection; Liver neoplasm; Experience