Abstract

Sensory neurons of C. elegans have signalling hubs called primary cilia, extending from dendritic endings, to sense and respond to the external environment. Cilia have a microtubule-based intraflagellar transport (IFT), which is essential for the growth and maintenance of the structure. The IFT proteins associated with cilia, have to be transported from the cell body to the cilia base, moving across the dendrites (10s of microns), where they assemble into IFT trains and cross a transition barrier to enter the cilia.

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