Abstract

SummaryA simplified tube neutralization test for assay of antibodies to Rous sarcoma virus and related avian leucosis viruses was described which appears to be suitable for differentiating serotypes and for surveys for naturally occurring antibodies against these viruses. The test was used in preliminary surveys for antibodies to Rous virus in sera of various species. Most hens in 3 commercial flocks of laying chickens were found to be positive for antibody. One of 3 hens without detectable antibodies was found to have RIF viremia. No antibodies were found in limited numbers of sera from turkeys, Japanese quail, pigeons or in sera from human subjects with or without leukemia.

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