Abstract
We read with great interest the paper of Raphael et al. [1] regarding the evaluation of the iterative method of optimal atrioventricular (AV) delay for cardiac resynchronization therapy (CRT). The paper addressed an important issue that iterative AV optimization is not executed reliably by experts. Such optimization is essentially important in CRT, which could reduce morbidity and mortality in patients with severe heart failure if the value is settled appropriately [2]. However, despite the fact that several methods have been proposed, AV delay is often programmed via an empirical method or left to a predefined value.
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