Abstract
A simple inexpensive solid-phase amino acid sequencing device has been constructed which uses nitrogen pressure for introducing or removing reagents to or from a reaction vessel. Although a thioacetylation procedure was employed in the operations reported here, any stepwise degradation scheme can be used simply by changing the contents of the reservoirs. Flexible programming has been achieved with a Tenor stepping-drum programmer. The results obtained from a 26-cycle degradation of the insulin B-chain are presented.
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