Abstract
The chlorination of the carboxylic acid unit of α-aminoacids is an important reaction in organic synthesis, and the resulting compounds are usually seen as reactive intermediate species. Herein we report a straightforward procedure to obtain [MCl6]− salts (M = Nb, 2a; Ta, 2b) of the L-proline-derivative (pyrrolidinium-2-carbonylchloride). These are stable up to 80 °C, in the solid state as well as in organic solvents. The X-ray structures determined for 2a,b include the first example of a crystallographically-characterized α-ammonium-acylchloride.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
