Abstract

A method for determining solubility that is fast and requires only a Büchner-type filter funnel, a 500-mL round-bottom flask, and an analytical balance is described. The loss in weight of a compound after suction extraction with one liter of water produces the solubility in grams per liter of water. Because the method involves only two weighings and no transfer of precipitate it is also potentially quite accurate. The method can be used for both very soluble compounds and for compounds with solubilities as low as several mg per liter of water.

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