Abstract
Reaction of 1 equivalent of N-“-acetyl-cis-4-azido-L-proline with 1 equivalent of an aldehyde and a catalytic amount of Pd-C under an H2 atmosphere cleanly and efficiently yields the corresponding N-“-acetylcis- 4-(N-γ-alkylamino)-L-proline derivative. Keywords: aminoproline, reductive amination, azide, aldehyde, secondary amine
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