Abstract

Accurate identification of the shape and position of organs and abnormal objects (e.g., tumors) in medical images plays an important role in surgical planning as well as in the diagnosis and prognosis of diseases. However, this is difficult to achieve from two-dimensional medical images as these images present inaccurate and ambiguous organ boundaries. Further, traditional image processing-based boundary detection methods such as the Canny edge detector and Sobel operator exhibit poor boundary detection performance for images with substantial noise. Recently, the use of deep learning has resulted in improvements in semantic segmentation in medical images. In this paper, we propose a generic boundary-aware loss function to facilitate the effective discernment of the boundaries of organs and abnormal objects in medical images. Specifically, the proposed loss function introduces a boundary area and assigns higher weights to the loss of pixels located in the boundary area than to those in the non-boundary areas, thereby promoting effective learning in the boundary area. The results of experiments conducted using public medical datasets comprising colon polyp, skin lesion, and chest X-ray data indicate that the standard loss functions, such as cross-entropy loss and Dice loss, combined with the proposed boundary-aware loss function, achieve comparable or better performance than those without the boundary-aware loss function.

Highlights

  • Distinguishing the boundary of each region of organs and abnormal objects of interest is essential when the segmentation results of such entities are used for diagnosing diseases

  • If k denotes the number of pixels located within the boundary area, the BA loss function calculates the loss values of k pixels in the boundary area and (n − k) pixels in the non-boundary area based on the mean square error (MSE) loss function, and weights are given for p1 and p2

  • The experimental results obtained using these public medical datasets showed that the existing loss functions, such as cross entropy loss and Dice loss, combined with the proposed boundary-aware loss function achieved comparable or better performance than those without the boundary-aware loss function depending on the dataset used

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Summary

INTRODUCTION

Distinguishing the boundary of each region of organs and abnormal objects of interest is essential when the segmentation results of such entities are used for diagnosing diseases. Deep learning-based image segmentation has been applied to detect the boundaries of organs and specific objects of interest with encouraging results [7]. A loss function is a crucial component in deep learning because it calculates the difference between the ground truth and the predicted value in the deep learning process. Lee: Simple Generic Method for Effective Boundary Extraction in Medical Image Segmentation. It calculates the loss value by squaring the difference between the value predicted by the CNN and the ground truth and using it for learning. This paper proposes a loss function to facilitate effective discernment of the boundaries of organs and abnormal objects (e.g., tumor) in 2D images.

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CONCLUSION
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