Abstract
Purpose: Knee osteoarthritis (OA) is a chronic disease with slow evolution. Kellgren and Lawrence (KL) classification is used to identify the radiographic stages of the disease, but has limited predictive validity of structural disease progression. We hypothesized that, in combination with KL, Osteoarthritis Research Society International (OARSI) Joint Space Narrowing (JSN) grades, permit a superior identification of structural progressors, i.e. patients with subsequent cartilage thickness loss.
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